We are still actively working on the spam issue.
You have failed to use Common Sense, and now your computer is infected. What do?
The Best Answer
Wipe the entire system, reformat the drive, re-install the OS. Once you are openly infected, there is no way you can ever be sure you still aren't harboring some kind of nasty botnet (the REAL kind, not the /g/ kind) even if you seem to have gotten rid of the most obvious symptoms.
But if you MUST...
If there are any toolbars or search addons listed in Programs and Features, try to uninstall them from there first. Sometimes that's enough to get rid of it.
Check your list of browser extensions and add-ons, remove anything suspicious, sometimes adware will install as a "managed" extension and chrome won't let you remove it, you'll have to delete the whole chrome folder in AppData and then reinstall.
Also run MSConfig and disable suspicious startup items that aren't supposed to be there. (Google the name if you're suspicious.)
If neither of those fix your problems, try scanning with Malwarebytes Anti-Malware, then if that doesn't fix it, try TDSSKiller and F.Secure Blacklight.